When fathers exercise, their future offspring may benefit, mouse study suggests

first_img Male mice that work out spawn healthier offspring than their lethargic counterparts, according to a new study. Whether the results hold true for humans remains uncertain, but they support the notion that some of the benefits of exercise are somehow passed on to the next generation.“The science is solid, and it’s pretty exciting,” says epigeneticist Sarah Kimmins of McGill University in Montreal, Canada, who wasn’t connected to the work.Scientists already know that a parent’s bad exercise or dietary habits can affect their offspring. Mothers who are obese during pregnancy, for example, give birth to children who are more likely to be obese as adults and develop metabolic illnesses such as cardiovascular disease. Another study found that male rats that snarfed high-fat chow fathered offspring that didn’t respond normally to glucose, a hallmark of type 2 diabetes.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)To determine whether the opposite is true, molecular exercise physiologist Kristin Stanford of The Ohio State University College of Medicine in Columbus and colleagues fed male mice a fat-rich diet for 3 weeks. One group of animals had access to running wheels, scampering nearly 6 kilometers per night on average, but the rest were couch potatoes. After dissecting some of the rodents to obtain samples of their sperm, the researchers allowed the remaining mice to mate.Stanford and her colleagues tracked the resulting offspring until they were a year old, about middle age for a mouse. Even though the offspring of exercising and nonexercising dads all ate a high-fat diet their entire lives and didn’t get any physical activity, the offspring of healthy fathers seemed to inherit their dads’ metabolism. The progeny of the runners showed a better response to increases in blood glucose and had lower insulin levels—both hallmarks of a sound metabolism—the researchers report today in Diabetes. “Exercise was completely negating the effect of a high-fat diet” on the offspring, Stanford says.The researchers suspect the offspring might inherit their dads’ metabolic condition through small RNA molecules in sperm. Previous studies have linked these molecules to changes in metabolism in the next generation. And indeed, the sperm of the lazy dads were loaded with fragments of transfer RNA. These molecules, when whole, are essential for synthesizing proteins, but how the fragments function is a mystery—they may modify protein production. The sperm of the exercisers, in contrast, had relatively few such fragments. Stanford and her colleagues still don’t know how the RNA shards affect an offspring’s metabolism, but they speculate that the pieces alter the growth or development of the young early in pregnancy.“It’s a well-executed paper,” says reproductive biologist Michelle Lane of the University of Adelaide in Australia, who wasn’t connected to the study. Previous research has only gauged the immediate effects of paternal exercise on young offspring, she says, but the fact that the researchers followed the mice for a year shows that “the possible impacts are maintained throughout life.”Lane cautions that researchers don’t know whether exercise provides the same benefits in people, so it may be too early for would-be fathers to start training for marathons. Nevertheless, Kimmins says, the study “provides hope that if men would exercise, they would have healthier children.” iStock.com/dra_schwartz By Mitch LeslieOct. 22, 2018 , 12:01 AM When fathers exercise, their future offspring may benefit, mouse study suggests This exercising mouse is helping itself and its offspring, a new study suggests.last_img read more

Syed Mushtaq Ali Trophy: Wriddhiman Saha dazzles for Bengal; Gautam Gambhir takes Delhi home

first_imgBengal wicketkeeper-batsman Wriddhiman Saha justified his selection to the national Test side for the one-off game against Bangladesh, by blasting a half-ton to guide his state side to a 10-wicket win over Assam in the Syed Mushtaq Ali T20 cricket tournament here on Wednesday.Chasing a modest 147 in the East zone match, Saha (74 not out) along with opener Sreevats Goswami (71 not out) comfortably took Bengal over the line with four overs to spare at the Eden Gardens here. Jharkhand lost to Tripura by 24 runsIn another East zone tie at the same venue, Jharkhand slumped to their third straight loss in the tournament when they lost to Tripura by 24 runs.Inspired by a 38-ball 74 from opener Udiyan Bose, Tripura went on to post a total of 192 before restricting Jharkhand to 168. (Syed Mushtaq Ali trophy: Shikhar Dhawan, Gautam Gambhir flop again as Himachal stun Delhi) Delhi managed to defeat Haryana by five wicketsMeanwhile, after losing two matches in a row, Delhi finally managed to defeat Haryana by five wickets in the North Zone inter-state clash at the Himachal Pradesh Cricket Association (HPCA) Stadium in Dharamsala.Skipper Gautam Gambhir ended his poor run by striking a 44-ball 61 to guide Delhi home with an over to spare in reply to Haryana’s paltry total of 114. Punjab edged past the Services by six runsIn another tie at the same venue, Punjab edged past the Services by six runs. Electing to bat after winning the toss, Punjab scored 129 before restricting the opposition to 123 in their stipulated 20 overs.advertisement Himachal Pradesh went down to Jammu and Kashmir by 18 runsAt Nadaun, hosts Himachal Pradesh went down to Jammu and Kashmir by 18 runs at the Atal Bihari Vajpayee Stadium.Himachal squandered a brilliant start with the ball as the match slipped from their hands during the chase, thanks to some poor shot selection and slow scoring rate.  Mumbai defeated Saurashtra by five wicketsIn the West zone clashes, Mumbai defeated Saurashtra by five wickets at the Moti Bagh Stadium in Vadodara while Baroda clinched the tie against Gujarat by 15 runs at the Reliance Stadium.Veteran all-rounder Abhishek Nayar stood out for Mumbai with an undefeated 47-ball 76 to overhaul Saurashtra’s 175 with two balls remaining. Baroda restricted Gujarat to 186/7On the other hand, riding on Deepak Hooda’s 51-ball 108, Baroda posted a mammoth 201 before restricting Gujarat to 186/7.last_img read more

APL Strengthens Oceania Trade with NZ2 Service

first_imgImage Courtesy: APLSingapore-based container shipping company APL, part of CMA CGM, plans to launch the New Zealand Express II (NZ2) service, starting from late December.The new weekly service, linking New Zealand and North Asian ports, is said to complement the company’s New Zealand Express (NZE) service.With the launch of the NZ2 service, APL said it will offer a network of six Oceania services that connect Asia with Australia and New Zealand.“APL introduced the new NZ2 service to serve the China-New Zealand market in a direct and more efficient way,” Tonnie Lim, APL Head of Intra-Asia Trade, said, adding that the new service will offer faster connectivity between the North Asia and Oceania markets.The NZ2 Service will call the ports of Shanghai, Ningbo, Chiwan (China), Kaohsiung (Taiwan), Brisbane (Australia), Auckland, Port Chalmers, Lyttelton, Napier, Tauranga (New Zealand), Hong Kong (Hong Kong) and Keelung (Taiwan).The first sailing of the new service is scheduled to commence from Shanghai on December 29, 2016.last_img read more

Meet The FirstTime GRAMMY Nominee HER On Being Born Into Music Why

first_img Artists React To Their 2019 GRAMMY Nominations 2019 GRAMMY Awards Red Carpet Lady GagaPhoto: Christopher Polk/Getty Images Album Of The Year vs. Record Of The Year Explained Twitter 2019 GRAMMY Awards Red Carpet 5 Ways BTS Won Our Hearts At The 2019 GRAMMYs News Cardi BPhoto: Dan MacMedan/WireImage Poll: Who Do You Want To See On The Red Carpet? Photo: Michael Loccisano/Getty Images Photo: Michael Loccisano/Getty Images Who Will Voters Pick For Best Latin Pop Album? TLC Photo: Alison Buck/Getty Images Relive GRAMMY Week 2019 In Pictures Best New Artist Nominees Revealed | 61st GRAMMYs Who’s Nominated For Song Of The Year? 61st GRAMMY Awards: Full Nominees & Winners List Cardi B, Post Malone Among 2019 GRAMMYs Performers Amy Winehouse Best New Artist winner for 2007 | Photo: Peter Macdiarmid/Getty Images Relive GRAMMY Week 2019 In Pictures Meet The GRAMMY Man: How GRAMMYs Are Made Cardi B, Post Malone Among 2019 GRAMMYs Performers 61st GRAMMYs: Here’s Your Apple Music Playlist BTSPhoto: Kevin Mazur/Getty Images Record Of The Year 61st GRAMMY Award Nominees Album Of The Year vs. Record Of The Year Explained Who’s Nominated For Song Of The Year? Cardi B, Post Malone Among 2019 GRAMMYs Performers Photo: studioEAST/Getty Images 2019 GRAMMY Awards Telecast | Photo Gallery Backstage At The 2019 GRAMMYs | Photo Gallery Facebook Record Of The Year 61st GRAMMY Award Nominees TLC Photo: Alison Buck/Getty Images 2019 GRAMMY Awards Premiere Ceremony Poll: Who Do You Want To See On The Red Carpet? Prev Next Who Is Eligible For The Best New Artist GRAMMY? Best New Artist Nominees Revealed | 61st GRAMMYs 61st GRAMMY Awards: Full Nominees & Winners List H.E.R.Photo by Prince Williams/Wireimage 5 Ways BTS Won Our Hearts At The 2019 GRAMMYs Cardi BPhoto: Dan MacMedan/WireImage Kacey MusgravesPhoto: Kevin Mazur/Getty Images “It feels like I’m exactly where I’m supposed to be,” the R&B singer/songwriter, who is up for five GRAMMYs, told usAna YglesiasGRAMMYs Feb 7, 2019 – 2:17 pm California native singer/songwriter H.E.R. may just be 21, but her honest and thoughtful approach to R&B, with personal lyrics and ’90s throwback slow-jam beats, reveal an old soul. Her smooth yet powerful voice offers insights on love and identity with vulnerability and plenty of straight-up feelings.While her music is communicative, and even her moniker is an acronym for “Having Everything Revealed,” the rising star still operates with an air of mystery. She has chosen to reveal minimal details about herself and, always pictured behind large sunglasses, seems to ask us to focus on her music first.We recently caught up with the talented multi-instrumentalist, who, as a first-time nominee, is up for five awards at the 61st GRAMMY Awards. (In addition to being nominated for the all-genre Best New Artist and Album Of The Year categories, she is also up for Best R&B Song, Best R&B Performance and Best R&B Album. H.E.R., the album in consideration, is a release combining her two EPs plus B-sides—she has yet to release a debut LP.)During our conversation, H.E.R. told us how grateful she is for all she’s achieved thus far, growing up in a musical household, the importance of keeping “real people” around you and what we can expect to hear on her forthcoming debut album. “I didn’t think I would get this far so soon, so I’m focusing on elevation and really dreaming bigger.” How did you first learn about your first GRAMMY nomination? When you found out you were up for five awards, what was your initial reaction?Oh my god! There were a lot of tears. I was with my tour squad; we had all just woken up early after a show. I was actually really sick, and kind of sad and down the day before. My manager gave us the news and it changed my entire mood and attitude. It made my day. I immediately called my mom, dad and sister. I was on cloud nine. Who Will Voters Choose For Best Alternative Album? 61st GRAMMY Awards John BillingsPhoto: Jesse Grant/WireImage/Getty Images Lady GagaPhoto: Christopher Polk/Getty Images Your five nominations include Best New Artist, along with Album of the Year and Best R&B Album. What does that recognition mean to you?It feels like I’m exactly where I’m supposed to be. It’s so easy to question your art, even to question what you’re doing, to question the path that you’re on. But this is such confirmation for me; “you’re exactly where you need to be, you’re doing all the right things.” It just feels amazing, it feels like I found my objective and I’m fulfilling it. I’m so blessed.Was there a moment when you were younger that made you want to make music? Were there other artists you admired that made you want to make R&B?Music was something that was a given for me, like out of the womb. At parties I was always the center of attention, singing and dancing and playing instruments. I never made that decision of “I’m going to do music.” My dad had a band that would rehearse in our living room, so all the instruments were in there and I gravitated towards them at a super-young age.My mom would try to find talent shows and festivals for me to be in around the Bay Area, even when I was only seven or eight years old, because she knew I loved to do it. It was never a career goal or what I was planning on doing as soon as I graduated high school. I just did it. It came super naturally to me.One artist I really respect is Alicia Keys. Because she plays piano and sings, and because I love instruments so much, she definitely paved the way for a young black musician and young black woman like me who wants to play instruments and find my voice in the industry. She played a big role.Related: 2019 GRAMMYs Host Alicia Keys: GRAMMY RewindI never really thought about the idea of being an R&B artist. R&B is kind of the core of everything, rhythm and blues. I grew up listening to a lot of soul and blues, so those influences shine through me. When I started making my first project, H.E.R. Vol. 1, it was so honest. It has a ’90s R&B influence, but you could feel the soul reflecting my background and where I came from.”Focus” is one of your songs up for a GRAMMY; the lyrics feel very personal and are really relatable. Can you talk about what that song means to you and how you think the honesty in your music helps you connect with fans?My music is my diary. When I’m writing a song it’s what I feel in that moment. With “Focus,” I was afraid to leave it on my first project because it was so personal for me, it’s so vulnerable. I was really young when I wrote it and was just feeling like, “put your phone down, pay attention to me.” It’s crazy how it’s gone deeper and resonated with so many women; women who are even five and ten years into marriage, and able to relate that small feeling I felt then.What’s your favorite part of being an artist?I don’t know if I have a favorite part of being an artist. I do love being onstage and performing with my band. I also love rehearsing with them and creating the show, that’s always a fun part. But there’s also nothing like being in the studio and being able to get back to myself and get back to my feelings. The studio is the place for me to really confront my feelings and get it all out. I love being in that space and creating, doing what I love, making art.Outside of music, how do you feel the success you’ve experienced in this past year has influenced or changed who you are?I’ve learned a lot about myself through my music and the way people perceive it, and the goal is for the success not to change me. I feel like the same person I was when I released it, I’ve just grown. The success has definitely taught me a lot about keeping real people around you, and about purpose. It’s taught me about the people and the things that you really need you to ensure success, and how important it is to keep those things around you and block out anything else, and about being positive.Also, seeing the world has given me a better perspective on life. The fact that I can travel around the world doing what I love is such a blessing. I’ve learned that traveling is such an important thing; there’s so many beautiful things out there and we get worried about such little things. 2019 GRAMMY Awards Telecast | Photo Gallery Poll: Who Do You Want To See On The Red Carpet? Meet The GRAMMY Man: How GRAMMYs Are Made Album Of The Year vs. Record Of The Year Explained 2019 GRAMMY Awards Premiere Ceremony Who Will Voters Pick For Best Pop Album? Who Will Voters Pick For Best Pop Album?center_img Poll: Who Will Voters Choose For Best Rap Album? Who Will Voters Choose For Best Alternative Album? Album Of The Year Nominees | 61st GRAMMY Awards Relive GRAMMY Week 2019 In Pictures Poll: Who Will Voters Choose For Best Rap Album? Artists React To Their 2019 GRAMMY Nominations Amy Winehouse Best New Artist winner for 2007 | Photo: Peter Macdiarmid/Getty Images BTSPhoto: Kevin Mazur/Getty Images 2019 GRAMMY Awards Premiere Ceremony Brandi Carlile, H.E.R. To Play The 61st GRAMMYs 61st GRAMMY Awards: Full Nominees & Winners List Kacey MusgravesPhoto: Kevin Mazur/Getty Images John BillingsPhoto: Jesse Grant/WireImage/Getty Images What are you most looking forward to about the GRAMMYs? How will you celebrate if you win?It’s going to be like a movie. The fact that I’m nominated for five [awards] is just, wow. And the fact that people are going to really see me, because as you know I haven’t revealed too much of myself. It’s going to be my first red carpet!After the GRAMMYs, I just want be with the ones I love and to reminisce. I love to think about memories and all the things that got me up to this point, so that would be celebratory, looking at old videos and old pictures of where I came from.Read More: Something About Her: The Mystery Of H.E.R.What’s on the horizon for H.E.R.—can we expect new music this year?Absolutely. I’m going to release a debut album, which I’m excited about. It’s crazy because my project that’s nominated for Album Of The Year is the combination of my two EPs. So there will be the new album and I’ll be touring more. Also, I’m starting a foundation called Bringing The Noise to help bring music back into schools that have lost their music programs. I’m really excited that I’m now in a position to be able to help people.There’s so much happening this year, I couldn’t even tell you. Like performing at Coachella! I didn’t think I would get this far so soon, so I’m focusing on elevation and really dreaming bigger.Meet The First-Time GRAMMY Nominee: TOKiMONSTA On Authenticity & Why ‘Lune Rouge’ Is “A Celebration Of Life” H.E.R.Photo by Prince Williams/Wireimage Photo: Michael Loccisano/Getty Images Who Will Voters Pick For Best Pop Album? Meet The GRAMMY Man: How GRAMMYs Are Made Who Is Eligible For The Best New Artist GRAMMY? Who Will Voters Pick For Best Rap Performance? Who Will Voters Pick For Best Rap Performance? Kacey MusgravesPhoto: Kevin Mazur/Getty Images John BillingsPhoto: Jesse Grant/WireImage/Getty Images BTSPhoto: Kevin Mazur/Getty Images Meet The First-Time GRAMMY Nominee: H.E.R. meet-first-time-grammy-nominee-her-being-born-music-why-rb-core-everything Who Will Voters Pick For Best Latin Pop Album? H.E.R.Photo by Prince Williams/Wireimage 2019 GRAMMY Awards Red Carpet 61st GRAMMYs: Here’s Your Apple Music Playlist Poll: Who Will Voters Choose For Best Rap Album? Artists React To Their 2019 GRAMMY Nominations Who Will Voters Pick For Best Latin Pop Album? Photo: studioEAST/Getty Images Brandi Carlile, H.E.R. To Play The 61st GRAMMYs Photo: studioEAST/Getty Images Record Of The Year 61st GRAMMY Award Nominees Album Of The Year Nominees | 61st GRAMMY Awards Who’s Nominated For Song Of The Year? Album Of The Year Nominees | 61st GRAMMY Awards Who Will Voters Pick For Best Rap Performance? Meet The First-Time GRAMMY Nominee: H.E.R. On Being Born Into Music & Why R&B Is “At The Core Of Everything” Lady GagaPhoto: Christopher Polk/Getty Images Backstage At The 2019 GRAMMYs | Photo Gallery Who Is Eligible For The Best New Artist GRAMMY? 61st GRAMMYs: Here’s Your Apple Music Playlist TLC Photo: Alison Buck/Getty Images Read more Email Cardi BPhoto: Dan MacMedan/WireImage Backstage At The 2019 GRAMMYs | Photo Gallery Amy Winehouse Best New Artist winner for 2007 | Photo: Peter Macdiarmid/Getty Images Who Will Voters Choose For Best Alternative Album? 5 Ways BTS Won Our Hearts At The 2019 GRAMMYs Brandi Carlile, H.E.R. To Play The 61st GRAMMYs Best New Artist Nominees Revealed | 61st GRAMMYs 2019 GRAMMY Awards Telecast | Photo Gallerylast_img read more

Bucket list trips strong Europe sales travel agent survey tracks trends

first_imgTags: Trend Watch PORTLAND — More than a third of clients seek out travel agents to help book ‘bucket list’ trips, according to a new poll.Conducted by Auto Europe, the survey polled travel agents in Canada and the U.S. about trends in the marketplace as well as their clients’ preferences in destination selection and transportation options while travelling.The majority of travel agents said they still find themselves helping smaller groups of two to three travellers who plan trips several months in advance, with fewer than 15% of clients planning last-minute vacations within a month before departure.Agents also said that more than 60% of their clients come to them with their destination in mind, with their ‘bucket list’ being the primary selection driver.The second most common source for choosing a destination was a recommendation from friends, family or travel influencers.More than three-quarters (76%) of travel agents also said they’re still seeing strong Europe sales, reporting that the same number or more of their clients plan to travel to Europe in the next 12 months compared to last year.More news:  Sunwing offers ultimate package deal ahead of YXU flights to SNU, PUJAuto Europe has a series of tools including Road Trip Planners and Travel Guides for top destinations for clients who want to rent a car in their destination.“We have a long-standing relationship with our travel agent partners and continually learn from them about travel and booking trends,” said Auto Europe’s Vice President of Sales, Robert Ardino. “We value their insights and we’re encouraged to hear that the main attributes that motivate agents to continue to use Auto Europe is our high level of service along with the availability of cars in locations convenient to client itineraries.”Ardino also noted that agent booking preferences in the survey ranged from online to over the phone to the GDS, “which illustrates the continued need for travel companies to support travel agents across all channels.” Bucket list trips, strong Europe sales: travel agent survey tracks trends Travelweek Group Posted bycenter_img Wednesday, August 31, 2016 Share << Previous PostNext Post >>last_img read more